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Chong, Anita S.
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overview My lab has had a long-standing interest in understanding the basis of immunological tolerance and humoral immunity following allogeneic transplantation. We have been collaborating extensively with Dr. Marisa Alegre in studying how infections prevent the induction of transplantation tolerance or destabilize established tolerance, and understanding the fundamental mechanisms of robust transplantation tolerance. We recently have developed new approaches to track a defined population of endogenous allospecific T (CD4+effectors (Th1 and Tfh), CD4+Tregs and CD8 effector) and B cells (Class I and Class II reactive), and are now asking how each of these subsets of cells behave under conditions of rejection, memory/sensitization and tolerance, with the goal of identifying new biomarkers of tolerance and rejection. We also actively investigating the behavior of memory alloreactive B cells in the setting of transplantation, and in identifying how these cells differ from naïve B cells, with the goal of identifying immunosuppressive and tolerance inducing strategies to control this clinically important subset of cells. We are conducting these studies in experimental rodent models, and also testing our findings in humans. These studies are performed in collaboration with Dr. Roger Sciammas at UCDavis, and the clinical transplant faculty at the University of Chicago and Ohio State University. In addition, we have stretched our research into the prevention of infections through vaccination, with the long-term goal of using this strategy as an indirect but cost-effective means of stabilizing tolerance. Towards this goal, my lab has been collaborating with Dr. Chris Montgomery, a physician scientist in the Department of Pediatrics, to identify sub-unit vaccine candidates and to investigate the immunobiology of protection from Staphylococcus aureus skin infections. My lab also has a strong program of collaborative research with Dr. Joel Collier, a bioengineer at Duke University, to develop of nanoparticulate adjuvant-free vaccines that can elicit protective immune responses with minimal inflammation. Such a vaccine that elicits minimal inflammation may be ideal for tolerant patients, as we now appreciate that inflammation can destabilize established tolerance.
One or more keywords matched the following items that are connected to Chong, Anita S.
Item TypeName
Concept Adjuvants, Immunologic
Concept Binding Sites, Antibody
Concept Alleles
Concept Amino Acid Sequence
Concept Administration, Sublingual
Concept Antigens, Surface
Concept Carcinoma, Squamous Cell
Concept Antibody Specificity
Concept Antilymphocyte Serum
Concept Base Sequence
Concept Binding Sites
Concept Cell Separation
Concept Complement System Proteins
Concept Cell-Free System
Concept Genes, Immunoglobulin
Concept Drug Synergism
Concept Graft Survival
Concept Disease Susceptibility
Concept Muscle, Smooth
Concept Hematopoietic Stem Cells
Concept Immune Sera
Concept Particle Size
Concept Mice, Inbred Strains
Concept Molecular Sequence Data
Concept Heat-Shock Proteins
Concept Neoplasm Staging
Concept Major Histocompatibility Complex
Concept Salivary Glands
Concept Stimulation, Chemical
Concept Portasystemic Shunt, Surgical
Concept Freund's Adjuvant
Concept Receptors, Cell Surface
Concept Intestine, Small
Concept Species Specificity
Concept Scrapie
Concept Staphylococcal Skin Infections
Concept Staphylococcus epidermidis
Concept Sensitivity and Specificity
Concept Swine
Concept Technetium Tc 99m Sulfur Colloid
Concept Sialoglycoproteins
Concept Skin
Concept Skin Diseases
Concept Societies, Medical
Concept Staphylococcal Infections
Concept Stearic Acids
Concept Stem Cells
Concept Tumor Stem Cell Assay
Concept Immunoglobulin Class Switching
Concept Hematopoietic Stem Cell Transplantation
Concept B-Lymphocyte Subsets
Concept Trimethoprim, Sulfamethoxazole Drug Combination
Concept Seroepidemiologic Studies
Concept Stem Cell Transplantation
Concept Rats, Sprague-Dawley
Concept T-Lymphocyte Subsets
Concept Protein Structure, Tertiary
Concept Genes, Reporter
Concept Oxidative Stress
Concept src-Family Kinases
Concept Methicillin-Resistant Staphylococcus aureus
Concept Reactive Oxygen Species
Concept Protein Structure, Secondary
Concept Single-Cell Analysis
Concept Sporozoites
Concept Oligonucleotide Array Sequence Analysis
Concept Sirolimus
Concept Hemangioma, Cavernous, Central Nervous System
Concept Severity of Illness Index
Concept Structure-Activity Relationship
Concept Sulfhydryl Reagents
Concept Pluripotent Stem Cells
Concept Nitric Oxide Synthase Type II
Concept Sex Factors
Concept Splanchnic Circulation
Concept Spleen
Concept Staphylococcus aureus
Concept Streptozocin
Concept Adaptor Proteins, Signal Transducing
Concept Insulin-Secreting Cells
Concept Survival Rate
Concept Skin Transplantation
Concept Lymphocyte Subsets
Concept Granulocyte Colony-Stimulating Factor
Concept Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Concept Nitric Oxide Synthase
Concept Tandem Repeat Sequences
Concept MAP Kinase Signaling System
Concept Vaccines, Subunit
Concept STAT1 Transcription Factor
Concept Syndecan-1
Concept STAT6 Transcription Factor
Concept Single-Chain Antibodies
Concept Cell Survival
Concept Drug Administration Schedule
Concept Drug Screening Assays, Antitumor
Concept Follow-Up Studies
Concept Mice, Mutant Strains
Concept Organ Specificity
Concept Prospective Studies
Concept Retrospective Studies
Concept Vaccines, Synthetic
Concept Signal Transduction
Concept Mice, SCID
Concept Macromolecular Substances
Concept Nucleotide Motifs
Academic Article Leflunomide, a novel immunomodulatory agent: in vitro analyses of the mechanism of immunosuppression.
Academic Article Regulation of B cell function by the immunosuppressive agent leflunomide.
Academic Article Vav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fc gamma RIIIA and is constitutively associated with a serine/threonine kinase.
Academic Article Daily determinations of serum lymphotoxin allows for accurate early diagnosis of hepatic allograft rejection.
Academic Article Immunosuppressive effects of leflunomide in a cardiac allograft model.
Academic Article Granulocyte colony-stimulating factor immunomodulation in the rat cardiac transplantation model.
Academic Article Prolongation of rat islet allograft survival by the immunosuppressive agent leflunomide.
Academic Article Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation.
Academic Article Delayed xenograft rejection in the concordant hamster heart into Lewis rat model.
Academic Article Effect of gene gun-mediated CTLA4IG and Fas ligand gene transfection on concordant xenogeneic islet graft rejection.
Academic Article In vivo effects of leflunomide on normal pancreatic islet and syngeneic islet graft function.
Academic Article Gene gun-mediated gene transfer and expression in rat islets.
Academic Article The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms.
Academic Article Effect of anti-CD4 monoclonal antibody combined with human CTLA4Ig on the survival of hamster liver and heart xenografts in Lewis rats.
Academic Article Anti-CD4 therapy in combined heart-kidney, heart-liver, and heart-small bowel allotransplants in high-responder rats.
Academic Article Successful xenotransplantation of adult porcine islets in NOD and BALB/c mice with leflunomide and cyclosporine.
Academic Article Leflunomide-based immunosuppression for porcine islet xenotransplantation.
Academic Article In vitro and in vivo mechanisms of action of the antiproliferative and immunosuppressive agent, brequinar sodium.
Academic Article In vivo activity of leflunomide: pharmacokinetic analyses and mechanism of immunosuppression.
Academic Article Control of lymphoproliferative and autoimmune disease in MRL-lpr/lpr mice by brequinar sodium: mechanisms of action.
Academic Article Inhibition of JAK3 and STAT6 tyrosine phosphorylation by the immunosuppressive drug leflunomide leads to a block in IgG1 production.
Academic Article Differential effect of leflunomide on concordant xenogeneic islet graft rejection and recurrence of autoimmune diabetes.
Academic Article Immunosuppression preventing concordant xenogeneic islet graft rejection is not sufficient to prevent recurrence of autoimmune diabetes in nonobese diabetic mice.
Academic Article In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: mechanisms of action.
Academic Article Tolerance of T-independent xeno-antibody responses in the hamster-to-rat xenotransplantation model is species-restricted but not tissue-specific.
Academic Article Non-depleting anti-CD4, but not anti-CD8, antibody induces long-term survival of xenogeneic and allogeneic hearts in alpha1,3-galactosyltransferase knockout (GT-Ko) mice.
Academic Article Protective effect of ischemic preconditioning on liver preservation-reperfusion injury in rats.
Academic Article FK506 treatment in combination with leflunomide in hamster-to-rat heart and liver xenograft transplantation.
Academic Article Differential immune response to carbohydrate epitopes on allo- and xenografts: implications for accommodation.
Academic Article The portosystemic shunt protects liver against ischemic reperfusion injury.
Academic Article Transcriptional regulation of Fas gene expression by GA-binding protein and AP-1 in T cell antigen receptor.CD3 complex-stimulated T cells.
Academic Article Histological characterization and pharmacological control of chronic rejection in xenogeneic and allogeneic heart transplantation.
Academic Article Onset of accumulation of PrPres in murine ME7 scrapie in relation to pathological and PrP immunohistochemical changes.
Academic Article Novel mechanism of inhibition of cytomegalovirus by the experimental immunosuppressive agent leflunomide.
Academic Article Differential immune responses to alpha-gal epitopes on xenografts and allografts: implications for accommodation in xenotransplantation.
Academic Article Nondepleting anti-CD4 but not anti-CD8 antibody induces long-term survival of xenogeneic and allogeneic hearts in alpha1, 3-galactosyl-transferase knock-out mice.
Academic Article Intact active bone transplantation synergizes with anti-CD40 ligand therapy to induce B cell tolerance.
Academic Article CTLA-41g in combination with anti-CD40L prolongs xenograft survival and inhibits anti-gal ab production in GT-Ko mice.
Academic Article Combination of antilymphocyte globulin and leflunomide leads to superior grafts.
Academic Article Experiences with leflunomide in solid organ transplantation.
Academic Article Development and characterization of anti-Gal B cell receptor transgenic Gal-/- mice.
Academic Article Allograft tolerance induced by intact active bone co-transplantation and anti-CD40L monoclonal antibody therapy.
Academic Article Direct killing of xenograft cells by CD8+ T cells of discordant xenograft recipients.
Academic Article The in vitro and in vivo effects of anti-galactose antibodies on endothelial cell activation and xenograft rejection.
Academic Article Skin graft survival in genetically identical cloned pigs.
Academic Article Role of CD4+ and CD8+ T cells in the rejection of concordant pancreas xenografts.
Academic Article Mouse-heart grafts expressing an incompatible carbohydrate antigen. II. Transition from accommodation to tolerance.
Academic Article Evidence that tilapia islets do not express alpha-(1,3)gal: implications for islet xenotransplantation.
Academic Article A mouse model for studying intrahepatic islet transplantation.
Academic Article Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation.
Academic Article Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors.
Academic Article Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration.
Academic Article Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen.
Academic Article Hyperacute rejection by anti-Gal IgG1, IgG2a, and IgG2b is dependent on complement and Fc-gamma receptors.
Academic Article Cellular therapies for type 1 diabetes.
Academic Article Toll-like receptor signaling in transplantation.
Academic Article Mechanistic study of malononitrileamide FK778 in cardiac transplantation and CMV infection in rats.
Academic Article The multiple facets of toll-like receptors in transplantation biology.
Academic Article TLR signals promote IL-6/IL-17-dependent transplant rejection.
Academic Article Concurrent antiviral and immunosuppressive activities of leflunomide in vivo.
Academic Article Glycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice.
Academic Article Decreased percentage of CD4+FoxP3+ cells in bronchoalveolar lavage from lung transplant recipients correlates with development of bronchiolitis obliterans syndrome.
Academic Article Seeing is believing: how the MIP-luc mouse can advance the field of islet transplantation and ß-cell regeneration.
Academic Article Alloantibodies prevent the induction of transplantation tolerance by enhancing alloreactive T cell priming.
Academic Article Peripheral deletion of mature alloreactive B cells induced by costimulation blockade.
Academic Article CD4+ T cells are sufficient to elicit allograft rejection and major histocompatibility complex class I molecule is required to induce recurrent autoimmune diabetes after pancreas transplantation in mice.
Academic Article The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele.
Academic Article Memory alloreactive B cells and alloantibodies prevent anti-CD154-mediated allograft acceptance.
Academic Article Expression of complement regulatory proteins in accommodated xenografts induced by anti-alpha-Gal IgG1 in a rat-to-mouse model.
Academic Article Matchmaking the B-cell signature of tolerance to regulatory B cells.
Academic Article Making a B-line for transplantation tolerance.
Academic Article IL-6 induced by Staphylococcus aureus infection prevents the induction of skin allograft acceptance in mice.
Academic Article Experimental models of B cell tolerance in transplantation.
Academic Article Plasma cell densities and glomerular filtration rates predict renal allograft outcomes following acute rejection.
Academic Article Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways.
Academic Article Splanchnic transplantation.
Academic Article The impact of infection and tissue damage in solid-organ transplantation.
Academic Article Modulating adaptive immune responses to peptide self-assemblies.
Academic Article Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope.
Academic Article TLR engagement prevents transplantation tolerance.
Academic Article Pharmacologically induced regression of chronic transplant rejection.
Academic Article Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide.
Academic Article American society of transplantation symposium on B cells in transplantation: harnessing humoral immunity from rodent models to clinical practice.
Academic Article Effect of leflunomide in control of acute rejection in hamster-to-rat cardiac xenografts.
Academic Article Cross-linking of CD45 on NK cells stimulates p56lck-mediated tyrosine phosphorylation and IFN-gamma production.
Academic Article Improved viability of hepatic allografts from fasted donors is associated with decreased peripheral TNF activity.
Academic Article Leflunomide immunosuppression in rat small intestinal transplantation.
Academic Article Prevention of allograft tolerance by bacterial infection with Listeria monocytogenes.
Academic Article Long-term control of alloreactive B cell responses by the suppression of T cell help.
Academic Article Leflunomide in experimental transplantation. Control of rejection and alloantibody production, reversal of acute rejection, and interaction with cyclosporine.
Academic Article Inactivation of Kupffer cells after prolonged donor fasting improves viability of transplanted hepatic allografts.
Academic Article Effect of leflunomide and cyclosporine on concordant xenogeneic islet transplantation in streptozotocin-induced and autoimmune diabetic mice.
Academic Article In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice.
Academic Article Quantitation of the changes in splenic architecture during the rejection of cardiac allografts or xenografts.
Academic Article Leflunomide controls rejection in hamster to rat cardiac xenografts.
Academic Article Induction of species-specific host accommodation in the hamster-to-rat xenotransplantation model.
Academic Article Inhibition of herpes simplex virus type 1 by the experimental immunosuppressive agent leflunomide.
Academic Article Lewis rat pancreas, but not cardiac xenografts, are resistant to anti-gal antibody mediated hyperacute rejection.
Academic Article The structure of anti-Gal immunoglobulin genes in naïve and stimulated Gal knockout mice.
Academic Article IFN-gamma production is specifically regulated by IL-10 in mice made tolerant with anti-CD40 ligand antibody and intact active bone.
Academic Article Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation.
Academic Article Antagonistic effect of toll-like receptor signaling and bacterial infections on transplantation tolerance.
Academic Article Three Strikes and You're Cured.
Academic Article Allograft ultraviolet-B irradiation in rat small intestinal transplantation.
Academic Article Multidrug resistance activity in human lymphocytes.
Academic Article Gamma-irradiated peripheral blood mononuclear cells can express LAK activity.
Academic Article Stimulation of IFN-gamma, TNF-alpha, and TNF-beta secretion in IL-2-activated T cells: costimulatory roles for LFA-1, LFA-2, CD44, and CD45 molecules.
Academic Article Monoclonal antibodies anti-CD3, anti-TCR alpha beta and anti-CD2 act synergistically with tumor cells to stimulate lymphokine-activated killer cells and tumor-infiltrating lymphocytes to secrete interferon gamma.
Academic Article T cell immunodeficiency in dyskeratosis congenita.
Academic Article Nonimmune lymphocyte-macrophage interaction. I. Quantification by an automated colorimetric assay.
Academic Article Tumor targets stimulate IL-2 activated killer cells to produce interferon-gamma and tumor necrosis factor.
Academic Article Phenotypic and functional analysis of lymphokine-activated killer (LAK) cell clones. Ability of CD3+, LAK cell clones to produce interferon-gamma and tumor necrosis factor upon stimulation with tumor targets.
Academic Article ICAM-1 and LFA-3 enhance the ability of anti-CD3 mAb to stimulate interferon gamma production in interleukin-2-activated T cells.
Academic Article Diverse multidrug-resistance-modification agents inhibit cytolytic activity of natural killer cells.
Academic Article IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression.
Academic Article Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin.
Academic Article Local inflammation exacerbates the severity of Staphylococcus aureus skin infection.
Academic Article Blocking of lymphokine activated killer (LAK) cell mediated cytotoxicity by cell-sized beads bearing tumor cell proteins.
Academic Article Natural killer cell cytotoxicity and the multidrug resistance gene.
Academic Article CD45-cross-linking stimulates IFN-gamma production in NK cells.
Academic Article Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients.
Academic Article Protective immunity against recurrent Staphylococcus aureus skin infection requires antibody and interleukin-17A.
Academic Article Transplantation tolerance and its outcome during infections and inflammation.
Academic Article Lessons and limits of mouse models.
Academic Article Microbes and allogeneic transplantation.
Academic Article Immune complex formation and in situ B-cell clonal expansion in human cerebral cavernous malformations.
Academic Article A self-adjuvanting supramolecular vaccine carrying a folded protein antigen.
Academic Article Memory B cells in transplantation.
Academic Article B cells assist allograft rejection in the deficiency of protein kinase c-theta.
Academic Article Gut microbiota elicits a protective immune response against malaria transmission.
Academic Article Reversing endogenous alloreactive B cell GC responses with anti-CD154 or CTLA-4Ig.
Academic Article Establishment of a global virtual laboratory for transplantation: a symposium report.
Academic Article Mechanisms and consequences of injury and repair in older organ transplants.
Academic Article Cell surface receptors for sulphated polysaccharides: a potential marker for macrophage subsets.
Academic Article Gradated assembly of multiple proteins into supramolecular nanomaterials.
Academic Article Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputs.
Academic Article New kid on the pretransplant block: IgG recognizing apoptotic cells.
Academic Article The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation.
Academic Article Spontaneous restoration of transplantation tolerance after acute rejection.
Academic Article Proteomic Identification of saeRS-Dependent Targets Critical for Protective Humoral Immunity against Staphylococcus aureus Skin Infection.
Academic Article Cutting Edge: CTLA-4Ig Inhibits Memory B Cell Responses and Promotes Allograft Survival in Sensitized Recipients.
Academic Article Importance of B Lymphocytes and the IgG-Binding Protein Sbi in Staphylococcus aureus Skin Infection.
Academic Article High-Fat Diet-Induced Obesity Enhances Allograft Rejection.
Academic Article The composition of the microbiota modulates allograft rejection.
Academic Article Cytotoxicity of prion protein peptide (PrP106-126) differs in mechanism from the cytotoxic activity of the Alzheimer's disease amyloid peptide, A beta 25-35.
Academic Article Delayed Cytotoxic T Lymphocyte-Associated Protein 4-Immunoglobulin Treatment Reverses Ongoing Alloantibody Responses and Rescues Allografts From Acute Rejection.
Academic Article Tracing Donor-MHC Class II Reactive B cells in Mouse Cardiac Transplantation: Delayed CTLA4-Ig Treatment Prevents Memory Alloreactive B-Cell Generation.
Academic Article Impact of Staphylococcus aureus USA300 Colonization and Skin Infections on Systemic Immune Responses in Humans.
Academic Article Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance.
Academic Article From Pipe Dream to Donor-Specific PC Elimination: Novel Ways to Target Alloantibodies.
Academic Article Adoptive Transfer of Tracer-Alloreactive CD4+ T Cell Receptor Transgenic T Cells Alters the Endogenous Immune Response to an Allograft.
Academic Article Virtual Global Transplant Laboratory Standard Operating Protocol for Donor Alloantigen-specific Interferon-gamma ELISPOT Assay.
Academic Article Erosion of Transplantation Tolerance After Infection.
Academic Article Transplantation tolerance: don't forget about the B cells.
Academic Article Tracking of TCR-Transgenic T Cells Reveals That Multiple Mechanisms Maintain Cardiac Transplant Tolerance in Mice.
Academic Article Evolving Approaches in the Identification of Allograft-Reactive T and B Cells in Mice and Humans.
Academic Article Successful Treatment of T Cell-Mediated Acute Rejection with Delayed CTLA4-Ig in Mice.
Academic Article Active immunotherapy for TNF-mediated inflammation using self-assembled peptide nanofibers.
Academic Article Modification of the clonogenic assay for the detection of lymphokine activated killer cell activity.
Academic Article The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate.
Academic Article An optimized protocol to quantify signaling in human transitional B cells by phospho flow cytometry.
Academic Article Ability of cell-sized beads bearing tumor cell membrane proteins to stimulate LAK cells to secrete interferon-gamma and tumor necrosis factor-alpha.
Academic Article Alone Again, Naturally: B Cells Encountering Antigen Without T cells.
Academic Article Nonimmune lymphocyte-macrophage interaction. II. Evidence that the interaction involves sulfated polysaccharide recognition.
Academic Article Equal Expansion of Endogenous Transplant-Specific Regulatory T Cell and Recruitment Into the Allograft During Rejection and Tolerance.
Academic Article New insights into the development of B cell responses: Implications for solid organ transplantation.
Academic Article Regulation of tumor necrosis factor secretion in leukocytes from alpha-1-antitrypsin deficient humans.
Academic Article Cytostatic and cytotoxic activity of lymphokine-activated killer cell supernatants.
Academic Article Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures.
Academic Article Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
Academic Article Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance.
Academic Article CTLA4-Ig in combination with FTY720 promotes allograft survival in sensitized recipients.
Academic Article Outstanding questions in transplantation: B cells, alloantibodies, and humoral rejection.
Academic Article Fifty Shades of Tolerance: Beyond a Binary Tolerant/Non-Tolerant Paradigm.
Academic Article Desensitization in the Era of Precision Medicine: Moving From the Bench to Bedside.
Academic Article Skin-restricted commensal colonization accelerates skin graft rejection.
Academic Article ITS finally here! The first International Transplant Science meeting jointly organized by AST, ESOT, and TTS.
Academic Article Resilience of T cell-intrinsic dysfunction in transplantation tolerance.
Academic Article Recommended Treatment for Antibody-mediated Rejection After Kidney Transplantation: The 2019 Expert Consensus From the Transplantion Society Working Group.
Academic Article The First International Transplant Science (ITS) Meeting.
Academic Article B cells as antigen-presenting cells in transplantation rejection and tolerance.
Academic Article Enabling sublingual peptide immunization with molecular self-assemblies.
Academic Article Reversing donor-specific antibody responses and antibody-mediated rejection with bortezomib and belatacept in mice and kidney transplant recipients.
Academic Article Inhibition of protective immunity against Staphylococcus aureus infection by MHC-restricted immunodominance is overcome by vaccination.
Academic Article Sensitization in transplantation: Assessment of risk (STAR) 2019 Working Group Meeting Report.
Academic Article The First ITS Meeting.
Academic Article Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
Academic Article Desensitizing highly sensitized heart transplant candidates with the combination of belatacept and proteasome inhibition.
Academic Article Mechanisms of organ transplant injury mediated by B cells and antibodies: Implications for antibody-mediated rejection.
Academic Article The Impact of COVID-19 on the State of Clinical and Laboratory Research Globally in Transplantation in May 2020.
Academic Article Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and TH17 responses.
Academic Article Sex matters: COVID-19 in kidney transplantation.
Academic Article Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in mice.
Academic Article Impaired T-Lymphocyte Responses During Childhood Staphylococcus aureus Infection.
Academic Article Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection.
Academic Article Incorporation of Sex and Gender Guidelines Into Transplantation Literature.
Academic Article The Women of FOCIS: Promoting Equality and Inclusiveness in a Professional Federation of Clinical Immunology Societies.
Academic Article Toward an understanding of allogeneic conflict in pregnancy and transplantation.
Academic Article Semiallogeneic Pregnancy: A Paradigm Change for T-cell Transplantation Tolerance.
Academic Article Oral alloantigen exposure promotes donor-specific tolerance in a mouse model of minor-mismatched skin transplantation.
Academic Article Linked sensitization by memory CD4+ T cells prevents costimulation blockade-induced transplantation tolerance.
Academic Article Host-versus-commensal immune responses participate in the rejection of colonized solid organ transplants.
Academic Article A multi-faceted approach to sex and gender equity in solid organ transplantation: The Women in Transplantation Initiative of The Transplantation Society.
Academic Article Sensitization in transplantation: Assessment of Risk 2022 Working Group Meeting Report.
Academic Article Tissue specificity drives protective immunity against Staphylococcus aureus infection.
Academic Article Joining Forces in Basic Science: ITS Meeting 2.0.
Academic Article Sugar-coated Antigens Generated During Pregnancy Mediate Fetomaternal Tolerance.
Academic Article Reduced Satb1 expression predisposes CD4+ T conventional cells to Treg suppression and promotes transplant survival.
Academic Article Navigating the Dobbs versus Jackson America for Patients with CKD and Kidney Transplants.
Concept Sugars
Concept Observational Studies as Topic
Academic Article State-of-the-art Meeting on Sex and Gender in Transplantation: The Female Perspective.
Academic Article Corrigendum to 'Sensitization in transplantation: Assessment of Risk 2022 Working Group Meeting Report' [American Journal of Transplantation 23 (2023) 133-149].
Academic Article A transitional B-cell cytokine biomarker for risk stratifying renal transplant patients with borderline rejection.
Academic Article Pregnancy programs epigenetic and transcriptional exhaustion in memory CD8+ T cells.
Academic Article MHC Tetramers Specifically Identify High- and Low-avidity Donor-specific B Cells in Transplantation Tolerance and Rejection.
Academic Article Sex as a biological variable: Mechanistic insights and clinical relevance in solid organ transplantation.
Academic Article Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection.
Academic Article A novel triptolide analog downregulates NF-?B and induces mitochondrial apoptosis pathways in human pancreatic cancer.
Academic Article Lung cDC1 and cDC2 dendritic cells priming naive CD8+ T cells in situ prior to migration to draining lymph nodes.
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